PAQR7
Function
Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432). Seems to act through a G(i) mediated pathway (PubMed:23763432). May be involved in oocyte maturation (PubMed:12601167). Involved in neurosteroid inhibition of apoptosis (PubMed:23161870). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed:23161870).
Sequence Similarities
Belongs to the ADIPOR family.
Tissue Specificity
Expressed in a wide range of tissues including ovary, testis, placenta, uterus and bladder.
Cellular localization
- Cell membrane
- Multi-pass membrane protein
Alternative names
MRPA, PAQR7, Membrane progestin receptor alpha, mPR alpha, Membrane progesterone P4 receptor alpha, Membrane progesterone receptor alpha, Progesterone and adipoQ receptor family member 7, Progestin and adipoQ receptor family member 7, Progestin and adipoQ receptor family member VII