Pax7
Developmental stage
Expressed specifically during the development of the nervous and muscular system.
Function
Transcription factor that is involved in the regulation of muscle stem cells proliferation, playing a role in myogenesis and muscle regeneration.
Post-translational modifications
Acetylation at Lys-105 and Lys-139 by KAT8 is required for high-level transcription factor activity (PubMed:34059674). Deacetylated by SIRT2 (PubMed:34059674).
Sequence Similarities
Belongs to the paired homeobox family.
Cellular localization
- Nucleus
Alternative names
Pax-7, Paired box protein Pax-7