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Function

Transcription factor required for normal development of thymus, parathyroid glands, ultimobranchial bodies, teeth, skeletal elements of skull and larynx as well as distal limbs.

Involvement in disease

Tooth agenesis, selective, 3

STHAG3

A form of selective tooth agenesis, a common anomaly characterized by the congenital absence of one or more teeth. Selective tooth agenesis without associated systemic disorders has sometimes been divided into 2 types: oligodontia, defined as agenesis of 6 or more permanent teeth, and hypodontia, defined as agenesis of less than 6 teeth. The number in both cases does not include absence of third molars (wisdom teeth).

None

The disease is caused by variants affecting the gene represented in this entry.

Cellular localization

  • Nucleus

Alternative names

Paired box protein Pax-9, PAX9

Target type

Proteins

Primary research area

Immunology & Infectious Disease

Molecular weight

36310Da

We found 2 products in 2 categories

Primary Antibodies

Target

Application

Reactive species

Proteins & Peptides

Target

Species of origin

Search our catalogue for 'PAX9' (2)

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