Component of pre-mRNA cleavage complex II, which promotes transcription termination by RNA polymerase II.
Phosphorylation at Ser-120 and/or Thr-121 by WNK1 weakens its association with POLR2A/RNA polymerase II, promoting transcript release from the chromatin template and mRNA export to the cytoplasm.
KIAA0824, PCF11, Pre-mRNA cleavage complex 2 protein Pcf11, Pre-mRNA cleavage complex II protein Pcf11
Proteins
Immunology & Infectious Disease
173050Da
We found 3 products in 1 category
ab220278
ab134391
ab222819