Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
Belongs to the peptidase S8 family. Furin subfamily.
Att-1, Nec-1, Nec1, Pcsk1, Neuroendocrine convertase 1, NEC 1, Furin homolog, PC3, Prohormone convertase 1, Propeptide-processing protease, Proprotein convertase 1, PC1
Proteins
Immunology & Infectious Disease
84174Da
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