PDCD11
Function
Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA.
Involved in the biogenesis of rRNA.
Cellular localization
- Nucleus
- Nucleolus
Alternative names
KIAA0185, PDCD11, Protein RRP5 homolog, NF-kappa-B-binding protein, Programmed cell death protein 11, NFBP