PDE1A

Function

Calcium/calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cGMP and cAMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP.

Sequence Similarities

Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.

Tissue Specificity

Several tissues, including brain, kidney, testes and heart.

Alternative names

Cam-PDE 1A, 61 kDa Cam-PDE, hCam-1, PDE1A

Database links

swissprot:P54750 omim:171890 genbank:NP_005010.2 entrezGene:5136