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PDZK1IP1

Function

Auxiliary protein of electrogenic Na(+)-coupled sugar symporter SLC5A2/SGLT2 and SLC5A1/SGLT1 (PubMed:34880493, PubMed:37217492, PubMed:38057552). Essential for the transporter activity of SLC5A2/SGLT2 but not SLC5A1/SGLT1 (PubMed:37217492).

Sequence Similarities

Belongs to the PDZK1-interacting protein 1/SMIM24 family.

Cellular localization

Alternative names

MAP17, PDZK1IP1, PDZK1-interacting protein 1, 17 kDa membrane-associated protein, Protein DD96

swissprot:Q13113 omim:607178 entrezGene:10158