Perilipin-2

Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets.

Acylated; primarily with C14, C16 and C18 fatty acids.

Phosphorylation at Tyr-232 by isoform 1 of CHKA (CHKalpha2) promotes dissociation from lipid droplets: dissociation is followed by recruitment of autophagosome machinery to lipid droplets and subsequent lipid droplet lipolysis.

Belongs to the perilipin family.

Milk lipid globules.

• Membrane
• Peripheral membrane protein
• Lipid droplet

ADFP, PLIN2, Perilipin-2, Adipophilin, Adipose differentiation-related protein, ADRP

• entrezGene:123
• omim:103195
• swissprot:Q99541

Proteins

Metabolism

48075Da