PFDN5
Function
Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC.
Sequence Similarities
Belongs to the prefoldin subunit alpha family.
Tissue Specificity
Highly expressed in pancreas and skeletal muscle and moderately in other tissues.
Cellular localization
- Isoform 1
- Nucleus
- Isoform 2
- Cytoplasm
- Isoform 3
- Nucleus
Alternative names
MM1, PFD5, PFDN5, Prefoldin subunit 5, Myc modulator 1, c-Myc-binding protein Mm-1