PFKFB3 phospho S461
Function
Catalyzes both the synthesis and degradation of fructose 2,6-bisphosphate.
Post-translational modifications
Phosphorylation by AMPK stimulates activity.
Sequence Similarities
In the C-terminal section; belongs to the phosphoglycerate mutase family.
Tissue Specificity
Ubiquitous.
Alternative names
PFK/FBPase 3, Renal carcinoma antigen NY-REN-56, iPFK-2, PFKFB3