Pgf

Function

Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It binds to the receptor FLT1/VEGFR-1. Also promotes cell tumor growth (By similarity).

Sequence Similarities

Belongs to the PDGF/VEGF growth factor family.

Cellular localization

• Secreted

Alternative names

Plgf, Pgf, Placenta growth factor, PlGF

Database links

swissprot:P49764 entrezGene:18654

Other research areas

• Immuno-oncology