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PGGT1B

Function

Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Known substrates include RAC1, RAC2, RAP1A and RAP1B.

Sequence Similarities

Belongs to the protein prenyltransferase subunit beta family.

Alternative names

Geranylgeranyl transferase type-1 subunit beta, Geranylgeranyl transferase type I subunit beta, Type I protein geranyl-geranyltransferase subunit beta, GGTase-I-beta, PGGT1B

swissprot:P53609 omim:602031 entrezGene:5229