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PHF20L1

Function

Is a negative regulator of proteasomal degradation of a set of methylated proteins, including DNMT1 and SOX2 (PubMed:24492612, PubMed:29358331). Involved in the maintainance of embryonic stem cells pluripotency, through the regulation of SOX2 levels (By similarity).

Cellular localization

Alternative names

CGI-72, PHF20L1, PHD finger protein 20-like protein 1

swissprot:A8MW92 swissprot:Q86U89 entrezGene:51105