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Function

Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.

Tissue specificity

Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and metastatic melanomas (at protein level).

Cellular localization

  • Cytoplasm
  • Cytoplasmic vesicle
  • Nucleus
  • Nucleolus
  • Colocalizes with intracellular vesicles.

Alternative names

PHRIP, TDAG51, PHLDA1, Pleckstrin homology-like domain family A member 1, Apoptosis-associated nuclear protein, Proline- and glutamine-rich protein, Proline- and histidine-rich protein, T-cell death-associated gene 51 protein, PQ-rich protein, PQR protein

Target type

Proteins

Primary research area

Immunology & Infectious Disease

Molecular weight

45016Da

We found 5 products in 1 category

Primary Antibodies

Target

Application

Reactive species

Search our catalogue for 'PHLDA1' (5)

Products

ab133654

Anti-PHLDA1 antibody [EPR6674]

Recombinant
RabMAb