PHLDB2

The PH domain mediates the binding to phosphoinositides.

Seems to be involved in the assembly of the postsynaptic apparatus. May play a role in acetyl-choline receptor (AChR) aggregation in the postsynaptic membrane (By similarity).

• Cytoplasm
• Cytoplasm
• Cell cortex
• Membrane
• Peripheral membrane protein
• Cell projection
• Podosome
• Translocates to the plasma membrane at high levels of PtdIns(3,4,5)P3. At low levels of PtdIns(3,4,5)P3 is translocated to vesicular compartments. Localized to the myotube podosome cortex that surrounds the core (By similarity).

LL5B, PHLDB2, Pleckstrin homology-like domain family B member 2, Protein LL5-beta

• entrezGene:90102
• omim:610298
• swissprot:Q86SQ0

Proteins

Immunology & Infectious Disease

142158Da