PHLDB2
Domain
The PH domain mediates the binding to phosphoinositides.
Function
Seems to be involved in the assembly of the postsynaptic apparatus. May play a role in acetyl-choline receptor (AChR) aggregation in the postsynaptic membrane (By similarity).
Cellular localization
- Cytoplasm
- Cytoplasm
- Cell cortex
- Membrane
- Peripheral membrane protein
- Cell projection
- Podosome
- Translocates to the plasma membrane at high levels of PtdIns(3,4,5)P3. At low levels of PtdIns(3,4,5)P3 is translocated to vesicular compartments. Localized to the myotube podosome cortex that surrounds the core (By similarity).
Alternative names
LL5B, PHLDB2, Pleckstrin homology-like domain family B member 2, Protein LL5-beta