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pig L-FABP

Domain

Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

Function

Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes. Binds cholesterol. Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.

Sequence Similarities

Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Cellular localization

Alternative names

Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP, FABP1

swissprot:P49924