PIGX
Function
Essential component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM (By similarity).
Pathway
Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.
Post-translational modifications
N-glycosylated.
Sequence Similarities
Belongs to the PIGX family.
Cellular localization
- Endoplasmic reticulum membrane
- Single-pass type I membrane protein
Alternative names
Phosphatidylinositol-glycan biosynthesis class X protein, PIG-X, PIGX