PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine.
Belongs to the phospholipase A2 family.
Abundantly expressed in heart, skeletal muscle, kidney, liver and pancreas.
PLA2G12, FKSG38, UNQ2519/PRO6012, PLA2G12A, Group XIIA secretory phospholipase A2, GXII sPLA2, sPLA2-XII, Phosphatidylcholine 2-acylhydrolase 12A
Proteins
Immunology & Infectious Disease
21067Da
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