PLA2G12A
Function
PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine.
Sequence Similarities
Belongs to the phospholipase A2 family.
Tissue Specificity
Abundantly expressed in heart, skeletal muscle, kidney, liver and pancreas.
Cellular localization
- Secreted
- Cytoplasm
Alternative names
PLA2G12, FKSG38, UNQ2519/PRO6012, PLA2G12A, Group XIIA secretory phospholipase A2, GXII sPLA2, sPLA2-XII, Phosphatidylcholine 2-acylhydrolase 12A