Plaur
Function
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA.
Tissue Specificity
Expressed in angiogenic endothelial cells (at protein level).
Cellular localization
- Isoform 1
- Cell membrane
- Lipid-anchor
- GPI-anchor
- Isoform 2
- Secreted
Alternative names
CD87, Urokinase plasminogen activator surface receptor, U-PAR, uPAR, Plaur