ple
Function
Plays an important role in the physiology of adrenergic neurons.
Pathway
Catecholamine biosynthesis; dopamine biosynthesis; dopamine from L-tyrosine: step 1/2.
Sequence Similarities
Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
Cellular localization
- Cytoplasm
- Perinuclear region
- Cell projection
- Axon
- Expressed in dopaminergic axons and axon terminals.
Alternative names
TH, CG10118, ple, Tyrosine 3-monooxygenase, Protein Pale, Tyrosine 3-hydroxylase