PLEKHB2
Domain
The PH domain specifically binds phosphatidylserine, which is enriched in recycling endosome membranes, it doesn't recognize PIPs.
Function
Involved in retrograde transport of recycling endosomes.
Cellular localization
- Recycling endosome membrane
- Peripheral membrane protein
- Specifically detected in tubulovesicular structures, and colocalizes with TFNR.
Alternative names
EVT2, PLEKHB2, Pleckstrin homology domain-containing family B member 2, PH domain-containing family B member 2, Evectin-2