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Function

May play a role in cell differentiation in the intestinal epithelium.

Tissue specificity

Enriched in colonic mucosa. The expression of A4 follows a gradient along the crypto-villus axis with the most abundant message occurring in the lower half of the crypt.

Cellular localization

  • Membrane
  • Multi-pass membrane protein

Alternative names

A4, PLP2, Proteolipid protein 2, Differentiation-dependent protein A4, Intestinal membrane A4 protein

Target type

Proteins

Primary research area

Immunology & Infectious Disease

Molecular weight

16691Da

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