POP7
Function
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:30454648, PubMed:9630247). Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465).
Sequence Similarities
Belongs to the histone-like Alba family.
Cellular localization
- Nucleus
- Nucleolus
- Cytoplasm
- Cytoplasmic granule
- Under stress conditions colocalizes with SMN1 in punctuated cytoplasmic granules.
Alternative names
RPP20, POP7, Ribonuclease P protein subunit p20, RNaseP protein p20, Ribonucleases P/MRP protein subunit POP7 homolog, hPOP7