POPDC2
Function
Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density.
Sequence Similarities
Belongs to the popeye family.
Tissue Specificity
Expressed predominantly in the heart and in the skeletal muscle.
Cellular localization
- Membrane
- Multi-pass membrane protein
- Cell membrane
- Sarcolemma
Alternative names
POP2, POPDC2, Popeye domain-containing protein 2, Popeye protein 2