POU3F1
Function
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') (By similarity). Acts as a transcriptional activator when binding cooperatively with SOX4, SOX11, or SOX12 to gene promoters (By similarity). Acts as a transcriptional repressor of myelin-specific genes (By similarity).
Sequence Similarities
Belongs to the POU transcription factor family. Class-3 subfamily.
Tissue Specificity
Expressed in embryonal stem cells and in the developing brain.
Cellular localization
- Nucleus
Alternative names
OCT6, OTF6, POU3F1, Octamer-binding protein 6, Octamer-binding transcription factor 6, POU domain transcription factor SCIP, Oct-6, OTF-6