PPAT
Function
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
Pathway
Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2.
Sequence Similarities
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
Tissue Specificity
Ubiquitously expressed.
Alternative names
GPAT, PPAT, Amidophosphoribosyltransferase, ATase, Glutamine phosphoribosylpyrophosphate amidotransferase