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PPIC

Function

PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding.

Sequence Similarities

Belongs to the cyclophilin-type PPIase family.

Tissue Specificity

Expressed in kidney, skeletal muscle, pancreas, heart, lung, liver and to a lower extent in brain.

Cellular localization

Alternative names

CYPC, PPIC, Peptidyl-prolyl cis-trans isomerase C, PPIase C, Cyclophilin C, Rotamase C

swissprot:P45877 entrezGene:5480 omim:123842