PPIC

Function

PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding.

Sequence similarities

Belongs to the cyclophilin-type PPIase family.

Tissue specificity

Expressed in kidney, skeletal muscle, pancreas, heart, lung, liver and to a lower extent in brain.

Cellular localization

• Cytoplasm

Alternative names

• CYPC
• PPIC
• CYPC
• Peptidyl-prolyl cis-trans isomerase C
• PPIase C
• Cyclophilin C
• Rotamase C

Database links

• entrezGene:5480
• omim:123842
• swissprot:P45877

Target type

Proteins

Molecular weight

22763Da