PPP1R2 phospho T72
Function
Inhibitor of protein-phosphatase 1.
Post-translational modifications
Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex (By similarity). Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex.
Sequence Similarities
Belongs to the protein phosphatase inhibitor 2 family.
Alternative names
IPP2, PPP1R2, Protein phosphatase inhibitor 2, IPP-2