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Papillary renal cell carcinoma

Function

May regulate cell cycle progression through interaction with MAD2L2.

Involvement in disease

A chromosomal aberration involving PRCC is found in patients with papillary renal cell carcinoma. Translocation t(X;1)(p11.2;q21.2) with TFE3.

Tissue specificity

Ubiquitous in fetal and adult tissues.

Cellular localization

  • Nucleus

Alternative names

TPRC, PRCC, Proline-rich protein PRCC, Papillary renal cell carcinoma translocation-associated gene protein

Target type

Proteins

Primary research area

Metabolism

Molecular weight

52418Da