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PRKY

Involvement in disease

A chromosomal aberration involving PRKY is a cause of sex reversal disorder. Translocation t(X;Y)(p22;p11) with PRKX. Chromosomal translocations proximal to PRKY account for about 30% of the cases of sex reversal disorder in XX males and XY females.

Sequence Similarities

Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

Tissue Specificity

Ubiquitous.

Alternative names

Putative serine/threonine-protein kinase PRKY, PRKY

swissprot:O43930 omim:400008 entrezGene:5616