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PRM1

Function

Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.

Post-translational modifications

Phosphorylated by SRPK1.

Sequence Similarities

Belongs to the protamine P1 family.

Tissue Specificity

Testis.

Cellular localization

Alternative names

Sperm protamine P1, Cysteine-rich protamine, PRM1

swissprot:P04553 omim:182880