Probable E3 ubiquitin-protein ligase HERC6
Developmental stage
Expressed in fetal brain.
Function
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
Pathway
Protein modification; protein ubiquitination.
Tissue Specificity
Detected in brain, heart, placenta and testis.
Cellular localization
- Cytoplasm
- Cytosol
Alternative names
Probable E3 ubiquitin-protein ligase HERC6, HECT domain and RCC1-like domain-containing protein 6, HECT-type E3 ubiquitin transferase HERC6, HERC6