Pros1
Function
Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
Post-translational modifications
The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
Tissue Specificity
Plasma.
Cellular localization
- Secreted
Alternative names
Pros, Stil, Sil, Vitamin K-dependent protein S