Prostaglandin E2 receptor EP2 subtype

Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.

Belongs to the G-protein coupled receptor 1 family.

Placenta and lung.

• Cell membrane
• Multi-pass membrane protein

Prostaglandin E2 receptor EP2 subtype, PGE receptor EP2 subtype, PGE2 receptor EP2 subtype, Prostanoid EP2 receptor, PTGER2

• entrezGene:5733
• entrezGene:5732
• omim:176806
• omim:176804
• swissprot:P43116
• swissprot:O00325

Proteins

Immuno-oncology

39761Da