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Protein C-ets-2

Function

Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.

Post-translational modifications

Phosphorylation by CDK10 at Ser-220 and Ser-225 creates a phosphodegron that targets ETS2 for proteasomal degradation.

Sequence Similarities

Belongs to the ETS family.

Cellular localization

Alternative names

Protein C-ets-2, ETS2

swissprot:P15036 entrezGene:2114 omim:164740