Protein Wnt-5b
Function
Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).
Post-translational modifications
Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
Sequence Similarities
Belongs to the Wnt family.
Cellular localization
- Secreted
- Extracellular space
- Extracellular matrix
Alternative names
Protein Wnt-5b, WNT5B