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Proto-oncogene FRAT1

Function

Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.

Post-translational modifications

Phosphorylated.

Sequence similarities

Belongs to the GSK-3-binding protein family.

Cellular localization

  • Cytoplasm

Alternative names

Proto-oncogene FRAT1, Frequently rearranged in advanced T-cell lymphomas 1, FRAT-1, FRAT1

Target type

Proteins

Primary research area

Oncology

Molecular weight

29093Da

We found 3 products in 1 category

Primary Antibodies

Target

Application

Reactive species

Search our catalogue for 'Proto-oncogene FRAT1' (3)

Products

ab108405

Anti-FRAT1 antibody [EPR3900]

Recombinant
RabMAb