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prpL

Function

Lysine-specific endoprotease (PubMed:12419815). Involved in corneal virulence.

Post-translational modifications

Experiments performed in E.coli. Processing of pro-endopeptidase to mature endopeptidase is probably autocatalytic, as mutations in the probable active site residues prevent processing, and purified inactive pro-endopeptidase disappears in the presence of active endopeptidase.

Sequence Similarities

Belongs to the peptidase S1 family.

Cellular localization

Alternative names

PA4175, prpL, Lysyl endopeptidase, Protease IV, PvdS-regulated endoprotease

swissprot:Q9HWK6