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PRPS2

Function

Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.

Pathway

Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1.

Sequence Similarities

Belongs to the ribose-phosphate pyrophosphokinase family.

Alternative names

Ribose-phosphate pyrophosphokinase 2, PPRibP, Phosphoribosyl pyrophosphate synthase II, PRS-II, PRPS2

swissprot:P11908 entrezGene:5634 omim:311860