PRRX2
Developmental stage
Higher expression in fetus than in adult.
Function
May play a role in the scarless healing of cutaneous wounds during the first two trimesters of development.
Sequence Similarities
Belongs to the paired homeobox family.
Tissue Specificity
In fetal skin, highest expression found in cells of mesodermal origin within the dermal papilla of the developing hair shaft. Not detected in epidermis or dermis. In adult skin, weakly expressed within the basal layers of the epidermis. Not expressed in dermis.
Cellular localization
- Nucleus
Alternative names
PMX2, PRX2, PRRX2, Paired mesoderm homeobox protein 2, Paired-related homeobox protein 2, PRX-2