PRSS22
Function
Preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA.
Sequence Similarities
Belongs to the peptidase S1 family.
Tissue Specificity
Expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung. Scarce in adult lung. Expressed at low levels in placenta, pancreas, prostate and thyroid gland.
Cellular localization
- Secreted
Alternative names
BSSP4, PRSS26, SP001LA, UNQ302/PRO343, PRSS22, Brain-specific serine protease 4, BSSP-4, Serine protease 22, Serine protease 26, Tryptase epsilon