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PRSS3

Function

Digestive protease that cleaves proteins preferentially after an Arg residue and has proteolytic activity toward Kunitz-type trypsin inhibitors.

Sequence Similarities

Belongs to the peptidase S1 family.

Tissue Specificity

Detected in pancreas and pancreatic fluid (at protein level) (PubMed:6698368). Expressed in pancreas and brain (PubMed:8294000). Detected in ileum (PubMed:12021776).

Cellular localization

Alternative names

PRSS4, TRY3, TRY4, PRSS3, Trypsin-3, Brain trypsinogen, Mesotrypsin, Mesotrypsinogen, Serine protease 3, Serine protease 4, Trypsin III, Trypsin IV

swissprot:P35030 omim:613578 entrezGene:5646