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Proteasome 26S S3/PSMD3

Function

Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

Sequence similarities

Belongs to the proteasome subunit S3 family.

Alternative names

26S proteasome non-ATPase regulatory subunit 3, 26S proteasome regulatory subunit RPN3, 26S proteasome regulatory subunit S3, Proteasome subunit p58, PSMD3

Target type

Proteins

Primary research area

Immuno-oncology

Molecular weight

60978Da

We found 4 products in 1 category

Primary Antibodies