PTGFRN
Function
Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity). In myoblasts, associates with tetraspanins CD9 and CD81 to prevent myotube fusion during muscle regeneration (By similarity).
Cellular localization
- Endoplasmic reticulum membrane
- Single-pass type I membrane protein
- Golgi apparatus
- trans-Golgi network membrane
- Single-pass type I membrane protein
Alternative names
CD315, CD9P1, EWIF, FPRP, KIAA1436, PTGFRN, Prostaglandin F2 receptor negative regulator, CD9 partner 1, Glu-Trp-Ile EWI motif-containing protein F, Prostaglandin F2-alpha receptor regulatory protein, Prostaglandin F2-alpha receptor-associated protein, CD9P-1, EWI-F