PTPN18
Function
Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues.
Sequence Similarities
Belongs to the protein-tyrosine phosphatase family. Non-receptor class 4 subfamily.
Tissue Specificity
Expressed in brain, colon and several tumor-derived cell lines.
Cellular localization
- Nucleus
- Cytoplasm
Alternative names
BDP1, PTPN18, Tyrosine-protein phosphatase non-receptor type 18, Brain-derived phosphatase