pyrE
Function
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
Pathway
Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.
Sequence Similarities
Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
Alternative names
LHK_03212, pyrE, Orotate phosphoribosyltransferase, OPRT, OPRTase