RAB3D

Function

Protein transport. Probably involved in regulated exocytosis (By similarity).

Post-translational modifications

Phosphorylation of Thr-86 in the switch II region by LRRK2 prevents the association of RAB regulatory proteins, including CHM and CHML.

Sequence similarities

Belongs to the small GTPase superfamily. Rab family.

Tissue specificity

Highly expressed in granulocytes of peripheral blood. Constitutively expressed at low levels in all hematopoietic cell lines investigated.

Cellular localization

• Cell membrane
• Lipid-anchor
• Cytoplasmic side

Alternative names

• GOV
• RAB16
• RAB3D
• GOV
• RAB16
• Ras-related protein Rab-3D

Database links

• entrezGene:9545
• omim:604350
• swissprot:O95716

Target type

Proteins

Primary research area

Oncology

Molecular weight

24267Da