RABEP2
Function
Plays a role in membrane trafficking and in homotypic early endosome fusion (PubMed:9524116). Participates in arteriogenesis by regulating vascular endothelial growth factor receptor 2/VEGFR2 cell surface expression and endosomal trafficking (PubMed:29425100). By interacting with SDCCAG8, localizes to centrosomes and plays a critical role in ciliogenesis (PubMed:27224062).
Sequence Similarities
Belongs to the rabaptin family.
Cellular localization
- Cytoplasm
- Early endosome
- Cytoplasm
- Cytoskeleton
- Microtubule organizing center
- Centrosome
- Cytoplasm
- Cytoskeleton
- Cilium basal body
Alternative names
RABPT5B, RABEP2, Rab GTPase-binding effector protein 2, Rabaptin-5beta