RABGEF1
Function
Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase (By similarity).
Post-translational modifications
Monoubiquitinated.
Cellular localization
- Cytoplasm
- Early endosome
- Recycling endosome
Alternative names
RABEX5, RABGEF1, Rab5 GDP/GTP exchange factor, RAP1, Rabaptin-5-associated exchange factor for Rab5, Rabex-5